| Name： | SCUTELLARIN |
| CAS： | 27740-01-8 |
| Synonyms： | 7-(BETA-D-GLUCOPYRANURON ; SCUTELLAREIN 7-O-GLUCURONIDE ; SCUTELLAREIN-7-GLUCURONIDE ; SCUTELLARIN ; SCUTELLAREIN-7-O-BETA-D-GLUCURONIDE ; 5,6-DIHYDROXY-2-(4-HYDROXYPHENYL)-4-OXO-4H-1-BENZOPYRAN-7-YL-BETA-D-GLUCOPYRANOSIDURONIC ACID ; 7-(BETA-D-GLUCOPYRANURONOSYLOXY)-5,6-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE ; BREVISCAPIN ; SCUTELLARIN B |
| MDL.： | MFCD01861503 |
| H bond acceptor： | 12 |
| H bond donor： | 7 |
| Smile： | c1cc(ccc1c2cc(=O)c3c(o2)cc(c(c3O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O |
| InChi： | InChI=1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1 |
| InChiKey： | InChIKey=DJSISFGPUUYILV-ZFORQUDYSA-N |
Property |
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| Comments： | ASSAY METHOD: HPLC BIOCHEM/PHYSIOL ACTIONS: SCUTELLARIN IS A FLAVONOID THAT EXHIBITS A NUMBER OF CARDIO- AND NEURO-PROTECTIVE EFFECTS. SCUTELLARIN INHIBITS P38 ACTIVITY, ERK PHOSPHORYLATION, AND TGF-BETA EXPRESSION AND FIBROSIS IN A RAT MYOCARDIAL INFARCT MODEL. IN A CEREBRAL ISCHEMIA-REPERFUSION MODEL, THE COMPOUND REDUCED INFARCT VOLUME AND NEUROLOGICAL DEFICITS BY INCREASING ENOS EXPRESSION WHILE INHIBITING THE INDUCTION OF INOS SHELF LIFE: LIMITED SHELF LIFE, EXPIRY DATE ON THE LABEL STORAGE TEMPERATURE: 2-8 DEG C WGK: 3 |
| Specification： | ANALYTICAL STANDARD |
Safety information |
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SCUTELLARIN
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