| Name： | PHOSPHORAMIDON DISODIUM SALT |
| CAS： | 119942-99-3 ;36357-77-4 |
| Synonyms： | PHOSPHORAMIDON DISODIUM SALT ; PHOSPHORAMIDON ; N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN ; PHOSPHATIDYL DIPEPTIDE ; PHOSPHORAMIDON SODIUM SALT, PROTEOMICS ; PHOSPHORAMIDON SODIUM SALT, MICROBIAL SOURCE ; PHOSPHORAMIDON SODIUM SALT ; N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP DISODIUM SALT ; PHOSPHORAMIDON SODIUM SALT, ULTRA PURE GRADE 90+% ; N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXY-PHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT ; N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, 2NA ; N-(ALPHA-RHAMNOPYRANOSYLPHOSPHONO)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT |
| MDL.： | MFCD00077870 |
| H bond acceptor： | 13 |
| H bond donor： | 6 |
| Smile： | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OP(=O)(N[C@@H](CC(C)C)C(=O)N[C@@H](Cc2c[nH]c3c2cccc3)C(=O)[O-])[O-])O)O)O.[Na+].[Na+] |
| InChi： | InChI=1S/C23H34N3O10P.2Na/c1-11(2)8-16(26-37(33,34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15;;/h4-7,10-12,16-20,23-24,27-29H,8-9H2,1-3H3,(H,25,30)(H,31,32)(H2,26,33,34);;/q;2*+1/p-2/t12-,16-,17-,18-,19+,20+,23-;;/m0../s1 |
| InChiKey： | InChIKey=OQKHVXFOYFBMDJ-ODIUWQMJSA-L |
Property |
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| Comments： | APPLICATION: IDENTIFICATION OF PHOSPHORAMIDON AS A METALLO-ENDOPEPTIDASE INHIBITOR WAS USED TO CHARACTERIZE ENDOTHELIN CONVERTING ENZYME AS A METALLO-ENDOPEPTIDASE. PHOSPHORAMIDON INCREASES THE PRODUCTION OF BETA-AMYLOID PROTEIN, BUT NOT AMYLOID PRECURSOR PROTEIN, INDICATING THAT ABNORMAL AMYLOID PROCESSING IN ALZHEIMER'S DISEASE MAY BE CARRIED OUT BY A METALLO-ENDOPEPTIDASE ASSAY METHOD: TLC IMPURITIES: OTHER NOTES: MODE OF BINDING OTHER NOTES: NATURALLY OCCURRING THERMOLYSIN INHIBITOR SOLUBILITY: ACETIC ACID: SOLUBLE 20 MG/ML, CLEAR, COLORLESS TO LIGHT YELLOW-GREEN STORAGE TEMPERATURE: -20 DEG C UNSPSC: 12352200 WGK: 3 |
Safety information |
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| WGK Germany： | 3 |
PHOSPHORAMIDON DISODIUM SALT
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