| Name： | CYCLOPHOSPHAMIDE MONOHYDRATE |
| CAS： | 6055-19-2 |
| Synonyms： | CPA ; CYTOXAN MONOHYDRATE ; 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE HYDRATE ; 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE ; BIS(2-CHLOROETHYL)PHOSPHORAMIDE CYCLIC PROPANOLAMIDE ESTER MONOHYDRATE ; ENDOXAN A MONOHYDRATE ; CYTOXAN ; ENDOXON ; N,N-BIS(BETA-CHLOROETHYL)-N',O-PROPYLENEPHOSPHORIC ACID ESTER AMIDE MONOHYDRATE ; N,N-BIS(2-CHLOROETHYL)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORIN-2-AMINE-2-OXIDE MONOHYDRATE ; 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE MONOHYDRATE ; CYCLOPHOSPHAMIDE MONOHYDRATE ; CYCLOPHOSPHANE MONOHYDRATE ; 2-[BIS(2-CHLOROETHYL)AMINO]-1,3,2LAMBDA(5)-OXAZAPHOSPHINAN-2-ONE HYDRATE ; CYCLOPHOSPHAMIDE MONOHYDRATE 98+% ; 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-1,3,2-OXAZAPHOSPHORIN-2-OXIDE MONOHYDRATE ; CYCLOPHOSPHANE ; BIS(2-CHLOROETHYL)PHOSPHORAMIDE CYCLIC PROPANOLAMIDE ESTER ; CYCLOPHOSPHAMID MONOHYDRATE ; CYCLOPHOSPHAMIDE ; CYCLOPHOSPHAMIDE HYDRATE |
| MDL.： | MFCD00149395 |
| H bond acceptor： | 4 |
| H bond donor： | 1 |
| Smile： | C1CNP(=O)(OC1)N(CCCl)CCCl.O |
| InChi： | InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2 |
| InChiKey： | InChIKey=PWOQRKCAHTVFLB-UHFFFAOYSA-N |
Property |
|
| Melting Point： | 49-51 DEG C(LIT) |
| Boiling Point： | >110 DEG C |
| Physical Property： | FLASHPOINT: 113 DEG C FLASHPOINT: 235.4 DEG F |
| Comments： | BIOCHEM/PHYSIOL ACTIONS: CYCLOPHOSPHAMIDE IS A CYTOTOXIC NITROGEN MUSTARD DERIVATIVE WIDELY USED IN CANCER CHEMOTHERAPY. IT CROSS-LINKS DNA, CAUSES STRAND BREAKAGE, AND INDUCES MUTATIONS. ITS CLINICAL ACTIVITY IS ASSOCIATED WITH A DECREASE IN ALDEHYDE DEHYDROGENASE 1 (ALDH1) ACTIVITY RIDADR: UN 3464 6.1/PG 3 RTECS: RP6157750 SOLUBILITY: H2O: SOLUBLE 0.1 G/ML, CLEAR, COLORLESS STORAGE TEMPERATURE: 2-8 DEG C UNSPSC: 12352200 WGK: 3 |
Safety information |
|
| Symbol： |
GHS06
GHS08
|
| Signal word： | Danger |
| Hazard statements： | H301-H350 |
| Precautionary statements： | P201-P301 + P310-P308 + P313 |
| hazard symbol： | T |
| Risk Code： | R:45-25 |
| Safe Code： | S:53-45 |
| WGK Germany： | 3 |
CYCLOPHOSPHAMIDE MONOHYDRATE
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