| Name： | ALPHA-AMANITIN |
| CAS： | 23109-05-9 |
| Synonyms： | AMANITA SP ; ASN-HYP-HYI-TRP-GLY-ILE-GLY-CYS [BRIDGE: 4-8] ; ALPHA-AMANITIN ; ALPHA-AMANITINE ; ALPHA-AMATOXIN ; A-AMANITIN ; AMANITIN, A- |
| MDL.： | MFCD00215842 |
| H bond acceptor： | 24 |
| H bond donor： | 13 |
| Smile： | CCC(C)[C@H]1C(=O)NCC(=O)N[C@@H]2CS(=O)c3c(c4ccc(cc4[nH]3)O)C[C@H](C(=O)NCC(=O)N1)NC(=O)[C@@H](NC(=O)C5CN(CC5O)C(=O)[C@H](NC2=O)CC(=O)N)[C@@H](C)[C@H](CO)O |
| InChi： | InChI=1S/C39H54N10O14S/c1-4-16(2)31-36(60)42-10-29(55)43-25-15-64(63)38-20(19-6-5-18(51)7-22(19)46-38)8-23(34(58)41-11-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-33(57)21-12-49(13-26(21)52)39(62)24(9-28(40)54)45-35(25)59/h5-7,16-17,21,23-27,31-32,46,50-53H,4,8-15H2,1-3H3,(H2,40,54)(H,41,58)(H,42,60)(H,43,55)(H,44,61)(H,45,59)(H,47,56)(H,48,57)/t16?,17-,21?,23+,24+,25+,26?,27-,31-,32-,64?/m0/s1 |
| InChiKey： | InChIKey=LSMJKGIULKKEQZ-SPUGEYPESA-N |
Property |
|
| Comments： | ASSAY METHOD: HPLC BIOCHEM/PHYSIOL ACTIONS: THE MAJOR TOXIC CONSTITUENT OF THE MUSHROOM, AMANITA PHALLOIDES, INHIBITS EUKARYOTIC RNA POLYMERASE II AND III, BUT DOES NOT INHIBIT RNA POLYMERASE I OR BACTERIAL RNA POLYMERASE. INHIBITS MAMMALIAN PROTEIN SYNTHESIS RIDADR: UN 3462 6.1/PG 2 RTECS: BD6195000 STORAGE TEMPERATURE: 2-8 DEG C UNSPSC: 12352200 WGK: 3 |
| Information： | BIOLOGICAL SOURCE: FROM AMANITA PHALLOIDES |
Safety information |
|
| Symbol： |
GHS06
GHS08
|
| Signal word： | Danger |
| Hazard statements： | H300-H310-H330-H373 |
| Precautionary statements： | P260-P264-P280-P284-P301 + P310-P302 + P350 |
| hazard symbol： | T+ |
| Risk Code： | R:26/27/28-33 |
| Safe Code： | S:36/37/39-45 |
| WGK Germany： | 3 |
ALPHA-AMANITIN
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